The project brings together public and private organisations from across Europe to perform collaborative research and development.
The interdisciplinary CHAIMELEON consortium is made up of 18 partners from 10 countries (Spain, Germany, France, Austria, United Kingdom, Israel, Italy, The Netherlands and Portugal) and constitutes a pan-European ecosystem of knowledge, infrastructures, biobanks and technologies on oncology, AI/in-silico and cloud computing addressed to health. The consortium includes hospitals, universities, R&D centres and private companies.
In all cases the P.I. belongs to the Radiology/Medical Imaging Department, which internally coordinates a multi-departmental group involving specialists in different areas (e.g. Oncology, Urology, Pathological Anatomy, Radiotherapy, Ethical Committee). The following 8 clinical partners in 6 European nations will provide CHAIMELEON with access to cases of lung, breast, colorectal and/or prostate cancers, according to the project plan:
- HULAFE (Spain): the Project Coordinator is one of the biggest public hospitals in Spain. The Biomedical and Imaging Research Group heads a multidisciplinary team focused on prostate cancer.
- ULS (Italy): The Radiology Unit at Sapienza University of Rome (ULS), headed by Prof Andrea Laghi, internationally renowned experts on Oncology Imaging, very experienced on colorectal cancer.
- PSD (Italy): The Radiology Unit at Policlinico San Donato is headed by Prof. Francesco Sardanelli, an international leading centre in breast imaging and breast cancer management.
- CERF (France): The Collège des Enseignants de Radiologie de France participates in this project as coordinator of the DRIM FRANCE AI, a national initiative addressed to building and operate the biggest qualified health imaging database in France, comprising a network of 32 main hospitals. Furthermore, Prof. Lassau, member of CERF and Head of Radiology at the Institut Gustave Roussy will coordinate CHAIMELEON works on lung cancer.
- UNIPI (Italy): The University Hospital of Pisa is responsible for the creation of a multi-omics Biobank including biomarkers form different sources. They are world-class experts in Imaging Biomarkers extraction, analysis and clinical validation, and in the standardization of imaging biobanks contents.
- CHUP (Portugal): The Porto University Hospital is one of the Portugal’s leading hospitals, awarded in the last five years as the one with the best performance in Portugal. Led by Dr. Manuela França. the Radiology Department is very experienced in cases of lung cancer and liver cancer.
- CHARITE (Germany): Both a hospital and one of the most research-intensive medical institutions in Germany. CHARITE will provide access to cases and also contribute with their expertise in AI methods for image annotation, segmentation and image-based decision support models.
- UM (Netherlands): The recently founded Precision Medicine Dpt., headed by Prof. Lambin, belongs to the umbrella organisation Maastricht University Medical Center+ (Univ. Maastritch + University Hospital Maastricht). Prof. Lambin is a pioneer in translational research on medical imaging, one of the fathers of the Radiomics and of the Distributed Learning concept for repositories of health data.
Universities, R&D Centres and Networks
- IMPERIAL (UK): World-class capabilities and expertise in AI applied to Medical Imaging: They will lead the development of tools for enhancing the reproducibility of radiomics features for cross-vendor/cross-institution image datasets. Although this research team is linked to Royal Brompton Hospital, their role in this project is as AI experts. Access to their clinical cases has been disregarded due to the Brexit issue which may difficult inclusion of data for British citizens in European biobanks.
- BGU (Israel): BGU’s Cybersecurity Research Center provides outstanding capabilities and expertise in the field of cybersecurity and the management of medical data in secure context. They are one of the most advanced R&D centres in this area, worldwide.
- UV (Spain): Led by Prof. Martinez (Privacy and digital transformation Chair Microsoft at the Department of Constitutional Law, Political and Administration Science, University of Valencia) offers outstanding experience in assessing compliance with GDPR and guidelines on Data Privacy.
- UPV (Spain): They provide access and management of cloud e-Infrastructures and high-level services for the management and processing of Medical Images. Adaptation of applications for data analytics in the context of medical data. Management of medical data in secure context and Privacy preservation.
- EIBIR (Austria): The European Institute for Biomedical Imaging Research is a non‐profit research organisation dedicated to coordinating biomedical imaging research. EIBIR has a vast experience in the dissemination and communication of results in the field of Medical Imaging.
- QUIBIM (Spain): a high-tech SME offering one the most advanced platforms for quantitative analysis of Imaging Biomarkers in the cloud (Quibim Precision). They have patented 7 imaging biomarkers for oncology diseases and CE marking for Quibim Precision as a Medical Device.
- GEHC (Germany): GE Health Care is one of the largest worldwide companies in Medical Imaging. They bring their experience in image acquisition, AI-enabled image reconstruction, quantitative imaging, physical modelling, equipment configurations, calibrations and quality standards.
- MAT (SPAIN): Matical is an expert consultancy company specialized in results exploitation and sustainability planning, expert in the management and implementation of large international projects, they will be in charge of Innovation management activities and future sustainability plans.
- MEDEX (France): Medexprim is an ICT SME specialized on big data in biomedical imaging. MEDEX provides automatization in identification, extraction and de-identification of large numbers of image sequences from images repositories and biobanks for secondary use in research.
- BAHIA (Spain): a technology company specialized in medical imaging, managing 8% of all medical images generated in Spain. Outstanding capabilities on AI applied to the management of medical imaging and experienced in promoting international standards for interoperability and connectivity.